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Breast | IHC quantification | ER/PR

0-click AI solution to detect and quantify ER/PR in breast cancer cells

Mindpeak Breast ER/PR is a software for automated image analysis of digital histopathology images of human invasive mamma carcinoma tissue samples. It is a stand-alone software module that supports the analysis of digital images acquired by scanning the fixed and ER/PR stained samples of invasive ductal and lobular carcinoma without the need for manual fine-tuning to your lab.

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Mindpeak Breast ER/PR is available in the EU as a CE-IVD marked medical device. Outside the EU, Mindpeak Breast ER/PR is Research Use Only, not for use in diagnostic procedures.

Find out how Breast ER/PR can work for you

Output

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Tumor cells are classified as not-stained (tumor negative) or stained (tumor positive). A corresponding positivity score is provided as the proportion of the number of tumor positive cells divided by the sum of tumor positive and tumor negative cells.

Workflow

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  • Step 1: Retrieve or select an image with the immunohistochemical ER/PR staining suited for diagnosis and automated analysis
  • Step 2: The result of Mindpeak Breast ER/PR whole slide displayed
  • Step 3: Review, adjust and correct the results of the automated analysis in an integrated interactive viewer module
  • Step 4: Conclude a final diagnostic decision

Required Software

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Mindpeak Breast ER/PR is a stand-alone software module for automated image analysis. For interaction with the medical device it must be integrated into an interactive image viewer software that allows the user to manually select or correct regions of interest for analysis with the medical device.

Required Hardware

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Mindpeak Breast ER/PR runs as a web service either in the cloud or on a dedicated on-premise server in the laboratory network. The cloud variant is specified and provided by Mindpeak or distribution partners and requires no additional hardware by the user. For minimum requirements for an on-premise solution, please contact us.

Supported samples

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The medical device supports the staining for ER through the SP1 assay from Roche Ventana and the EP1 assay from Agilent Dako, as well as for PR through the clone 16 assay from Leica Biosystems, the clone 1E2 assay from Roche Ventana and the clone 1294 assay from Agilent Dako.

Performance

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In conclusion of the identification, review, assessment, and analysis of the performance of the medical device, the medical device is considered to conform to the general safety and performance requirements according to the IVDD. For more information, please click here to see our study results.

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Detection and quantification of breast cancer cells in zero clicks

Identification & Quantification

Mindpeak Breast ER/PR detects and classifies cells into positively stained tumor and unstained tumor cells. One of its great advantages is its ability to differentiate between tumorous and non-tumorous structures, improving your scoring in the tumor microenvironment.

0-Click

Image pre-calculation in the background allows instant visualization of all ER/PR detected and classified cells. Just load the digital slide and you are done!

Lab Independent

The reliability of Mindpeak Breast ER/PR is unique: it provides accurate results even in challenging contexts as it was
developed with typical lab-specific variations in mind, such as slide preparation, staining and imaging.

Easy Integration

Mindpeak Breast ER/PR supports a broad range of scanners and can easily be integrated into existing workflows.

Find out how Breast ER/PR can work for you

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